Titlebook: Antiviral Strategies; Hans-Georg Kräusslich,Ralf Bartenschlager Book 2009 Springer-Verlag Berlin Heidelberg 2009 Antiviral Drug.DNA.Drug R

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书目名称Antiviral Strategies年度引用学科排名

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Viral Protease Inhibitors,hese have made the most significant advances in the recent past. Thus, we discuss the biochemistry of HIV-1 protease, inhibitor development, clinical use of inhibitors, and evolution of resistance. Since many different viruses encode essential proteases, it is possible to envision the development of

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Anti-Influenza Drugs: The Development of Sialidase Inhibitors, annum as a result of viral infections alone. The scourge of influenza virus has plagued mankind throughout the ages. The fact that new viral strains emerge on a regular basis, particularly out of Asia, establishes a continual socio-economic threat to mankind. The arrival of the highly pathogenic av

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Inhibitors of Viral Entry,rs exert their biological properties by inhibiting protein—protein interactions either within the viral envelope (Env) glycoproteins or between viral Env and host-cell receptors. The nature of resistance to entry inhibitors also differs from compounds inhibiting enzymatic targets due to their differ

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Interferons and Their Use in Persistent Viral Infections,ned, fully sequenced and IFN-α was produced in recombinant form. Recombinant IFN-α is now used as the basis for treatment of chronic hepatitis C virus infection and can also be used to treat certain forms of chronic hepatitis B virus infections. IFNs have also been used in other viral infections, al

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Nucleic Acids-Based Therapeutics in the Battle Against Pathogenic Viruses,nse oligonucleotides, ribozymes, DNAzymes, and aptamers can be designed to trigger the sequence-specific inhibition of particular mRNA transcripts, including viral genomes. However, difficulties with their efficiency, off-target effects, toxicity, delivery, and stability halted the development of nu

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Titlebook: Antiviral Strategies; Hans-Georg Kräusslich,Ralf Bartenschlager Book 2009 Springer-Verlag Berlin Heidelberg 2009 Antiviral Drug.DNA.Drug R

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